Evidence & experience

Research that travels beyond the laboratory.

Our analytical methods have been tested across demanding scientific, pharmaceutical, chemical, food, environmental and data-rich applications.

DiKnow’s work is supported by a substantial record of peer-reviewed research and practical analytical applications.

These publications demonstrate experience in multivariate analysis, artificial intelligence, spectroscopy, chromatography, pharmaceutical science, process analysis and predictive modelling. Publication metadata has been carefully consolidated from the existing DiKnow research record; external links open publisher or DOI records where available.

  1. McAdam, K. G., Tetteh, J., Bishop, L., Digard, H., Côté, J., Lubbe, S. & Liu, C. (2020). A combined study of headspace volatiles using human sensory, mass spectrometry and chemometrics. Scientific Reports, 10, Article 7773.
    View publication ↗
  2. Davies, A., Nicol, J. T. G., Liu, C., Tetteh, J. & McAdam, K. (2018). Identification of volatiles from heated tobacco biomass using direct thermogravimetric analysis–mass spectrometry and target factor analysis. Thermochimica Acta, 668, 132–141.
    View publication ↗
  3. Boateng, J. S., Pawar, H. V. & Tetteh, J. (2015). Evaluation of in vitro wound adhesion characteristics of composite film and wafer-based dressings using texture analysis and FTIR spectroscopy: a chemometrics factor analysis approach. RSC Advances, 5(129), 107064–107075.
    View publication ↗
  4. Pawar, H. V., Boateng, J. S., Ayensu, I. & Tetteh, J. (2014). Multifunctional medicated lyophilised wafer dressing for effective chronic wound healing. Journal of Pharmaceutical Sciences, 103(6), 1720–1733.
    View publication ↗
  5. Giovino, C., Ayensu, I., Tetteh, J. & Boateng, J. S. (2013). An integrated buccal delivery system combining chitosan films impregnated with peptide-loaded PEG-b-PLA nanoparticles. Colloids and Surfaces B: Biointerfaces, 112, 9–15.
    View publication ↗
  6. Asare-Addo, K., Conway, B. R., Larhrib, H., Levina, M., Rajabi-Siahboomi, A. R., Tetteh, J., Boateng, J. & Nokhodchi, A. (2013). The effect of pH and ionic strength of dissolution media on in-vitro release of two model drugs of different solubilities from HPMC matrices. Colloids and Surfaces B: Biointerfaces, 111, 384–391.
    View publication ↗
  7. Pawar, H. V., Tetteh, J. & Boateng, J. S. (2013). Preparation, optimisation and characterisation of novel wound-healing film dressings loaded with streptomycin and diclofenac. Colloids and Surfaces B: Biointerfaces, 102, 102–110.
    View publication ↗
  8. McAuley, W. J., Chavda-Sitaram, S., Mader, K. T., Tetteh, J., Lane, M. E. & Hadgraft, J. (2013). The effects of esterified solvents on the diffusion of a model compound across human skin: an ATR-FTIR spectroscopic study. International Journal of Pharmaceutics, 447(1–2), 1–6.
    View publication ↗
  9. Boateng, J. S., Pawar, H. V. & Tetteh, J. (2013). Polyox and carrageenan-based composite film dressing containing antimicrobial and anti-inflammatory drugs for effective wound healing. International Journal of Pharmaceutics, 441, 181–191.
    View publication ↗
  10. Barontini, F., Tugnoli, A., Cozzani, V., Tetteh, J., Jarriault, M. & Zinovik, I. (2013). Volatile products formed in the thermal decomposition of a tobacco substrate. Industrial & Engineering Chemistry Research, 52(42), 14984–14997.
    View publication ↗
  11. Zand, N., Chowdhry, B. Z., Pullen, F. S., Snowden, M. J. & Tetteh, J. (2012). Simultaneous determination of riboflavin and pyridoxine by UHPLC/LC–MS in UK commercial infant meal food products. Food Chemistry, 135, 2743–2749.
    View publication ↗
  12. Giovino, C., Ayensu, I., Tetteh, J. & Boateng, J. S. (2012). Development and characterisation of chitosan films impregnated with insulin-loaded PEG-b-PLA nanoparticles (NPs): a potential approach for buccal delivery of macromolecules. International Journal of Pharmaceutics, 428, 143–151.
    View publication ↗
  13. Pawar, H. V., Tetteh, J. & Boateng, J. S. (2012). Preparation and evaluation of streptomycin and diclofenac-loaded mucoadhesive films for wound healing. Wound Repair and Regeneration, 20(2), A34.
    View publication ↗
  14. Tortoe, C., Orchard, J., Beezer, A. & Tetteh, J. (2011). Application of radial basis function network with a Gaussian function of artificial neural networks in osmo-dehydration of plant materials. Journal of Artificial Intelligence, 4(4), 233–244.
    View publication ↗
  15. McAuley, W. J., Mader, K. T., Tetteh, J., Lane, M. E. & Hadgraft, J. (2010). ATR-FTIR spectroscopy and spectroscopic imaging of solvent and permeant diffusion across model membranes. European Journal of Pharmaceutics and Biopharmaceutics, 74, 413–419.
    View publication ↗
  16. Zand, N., Zotor, F. B., Chowdhry, B., Tetteh, J., Wray, D. & Amuna, P. (2010). Determination of mineral content of commercial infant foods in the United Kingdom. Proceedings of the Nutrition Society, 69(OCE6).
    View publication ↗
  17. McAuley, W. J., Mader, K. T., Tetteh, J., Lane, M. E. & Hadgraft, J. (2009). Simultaneous monitoring of drug and solvent diffusion across a model membrane using ATR-FTIR spectroscopy. European Journal of Pharmaceutical Sciences, 38, 378–383.
    View publication ↗
  18. Zotor, F. B., Amuna, P., Tetteh, J. & Ndanu, T. (2009). Age and gender influences on sensory perceptions of novel low-cost nutrient-rich food products developed using traditional Ghanaian ingredients. Annals of Nutrition & Metabolism, 54(3), 247–248.
    View publication ↗
  19. Russeau, W., Mitchell, J., Tetteh, J., Lane, M. E. & Hadgraft, J. (2009). Permeation of model formulations and commercial ibuprofen formulation in Carbosil® and human skin using ATR-FTIR and multivariate spectral analysis. International Journal of Pharmaceutics, 374, 17–25.
    View publication ↗
  20. Tetteh, J., Mader, K. T., Andanson, J.-M., McAuley, W. J., Lane, M. E., Hadgraft, J., Kazarian, S. G. & Mitchell, J. C. (2009). Local examination of skin diffusion using FTIR spectroscopic imaging and multivariate target factor analysis. Analytica Chimica Acta, 642, 246–256.
    View publication ↗
  21. Tortoe, C., Orchard, J., Beezer, A. & Tetteh, J. (2008). Artificial neural networks in modelling osmotic dehydration of foods. Journal of Food Processing and Preservation, 32, 270–285.
    View publication ↗
  22. O’Neill, M. A., Beezer, A. E., Tetteh, J., Gaisford, S. & Dhuna, M. (2007). Application of chemometric analysis to complexity in isothermal calorimetric data. The Journal of Physical Chemistry B, 111(28), 8145–8149.
    View publication ↗
  23. Snell, C., Tetteh, J. & Evans, I. H. (2005). Phylogeography of the pool frog (Rana lessonae Camerano) in Europe: evidence for native status in Great Britain and for an unusual postglacial colonisation route. Biological Journal of the Linnean Society, 85(1), 41–51.
    View publication ↗
  24. Dias, M., Hadgraft, J., Raghavan, S. L. & Tetteh, J. (2004). The effect of solvent on permeant diffusion through membranes studied using ATR-FTIR and chemometric data analysis. Journal of Pharmaceutical Sciences, 93(1), 186–196.
    View publication ↗
  25. Chowdhry, B. Z., Mendham, A. P., Tetteh, J. & Withnall, R. (2002). Kinetic resonance Raman spectroscopy of the Briggs–Rauscher oscillator. ChemPhysChem, 3(5), 443–446.
    View publication ↗
  26. Metcalfe, E. & Tetteh, J. (2001). Combustion toxicity and chemometrics. ACS Symposium Series, 797, 321–333.
    View publication ↗
  27. Jackson, M., Kim, K., Tetteh, J., Mansfield, J. R., Dolenko, B., Somorjai, R. L., Orr, F. W., Watson, P. H. & Mantsch, H. H. (1998). Cancer diagnosis by infrared spectroscopy: methodological aspects. Proceedings of SPIE, 3257, 24–34.
    View publication ↗
  28. Tetteh, J., Metcalfe, E., Howells, S., Withnall, R., Ames, S. & Vollam, S. (1996). Orthogonal noise annihilation for FTIR spectroscopy in fire-gas analysis. Fire and Materials, 20(1), 51–59.
    View publication ↗